Tobramycin belongs to a group of medicines known as aminoglycoside antibiotics.

It is used for the treatment of bacterial infections of the surface of the eye and eyelids, such

as conjunctivitis and blepharitis.

Do not use Tobracin if:

You are allergic to tobramycin, or any of the other ingredients listed in section 6.

In children under the age of 1 year.

The expiry date has passed.

Are wearing contact lenses.

You suffer from liver or kidney disease.

Tell your doctor if you are taking any other antibiotic medicines by mouth or by injection.

As with any antibiotic, use of Tobracin for a long time may lead to other infections.

Your symptoms get worse or suddenly return tell your doctor.

Do not stop using Tobracin or lower the dosage because you are feeling better, unless

advised by your doctor.

If you are pregnant or might get pregnant, or if you are breast-feeding a baby, talk to your

doctor before you use Tobracin.

Driving and using machines

You may find that your vision is blurred for a time just after you use Tobracin. Do not drive

or use any machines unless your vision is clear.

Using other medicines

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines,

including medicines obtained without a prescription.

If you are using other eye drops, wait at least 5-10 minutes after putting in Tobracin before

using the other drops. Put all your eye drops in before using any eye ointment.

Some medicines and Tobracin may interfere with each other. These include:

Topical beta lactam type antibiotics

These medicines may be affected by Tobrabin, or may affect how well it works. You may

need different amounts of your medicines, or you may need to take different medicines. Your

doctor or pharmacist has more information on medicines to be careful with or avoid while

using this medicine.

How much to use:

For eye drops: The usual dose in adults and children 1 year and older is 1 drop in your

eye(s), twice a day for 7 days.

In severe infections, this may be increased to 1 drop 4 times a day for the first day, followed

by 1 drop twice a day for 6 days.

For eye ointment: In mild to moderate infections, put small amount in the affected eye(s)

two or three times per day.

In severe infections put small amount in the affected eye(s) every three to four hours.

Do not stop using Tobracin before your doctor advises, even if your symptoms improve.

Always use Tobracin exactly as your doctor has told you. You should check with your

doctor or pharmacist if you are not sure.

Wash your hands before you start.

Twist off the bottle/tube cap.

Hold the bottle/tube pointing down, between your thumb and fingers.

Tilt your head back.

Pull down your lower eyelid with a finger, until there is a ‘pocket’ between the eyelid and

your eye. The drop/ointment will go in here.

Bring the bottle/tube tip close to the eye. Do this in front of a mirror if it helps.

Do not touch your eye or eyelid, surrounding areas or other surfaces with the dropper/tube

tip. It could infect the drops/ointment.

Gently press on the base of the bottle/tube to release the drop/ointment.

Don’t squeeze the bottle/tube, only a gentle press on the bottom is needed.

If you use drops/ointment in both eyes, repeat the steps for your other eye.

Making sure that the drop/ointment remains within the eye, slowly close your eye without

blinking. Keep your eye closed for 1 to 2 minutes.

- If a drop or ointment misses your eye, try again.

If you forget to use Tobracin, do not worry, just use it as soon as possible.

However, if it is almost time for your next dose, skip the missed dose and go back to your

normal dosing schedule. Do not take a double dose to make up.

If you take too much Tobracin

If you accidentally put too much Tobracin in your eye(s), immediately rinse your eye(s)

with warm water, and call your doctor or go to the emergency room at the near hospital.

Like all medicines, Tobracin can cause side effects, although not everybody gets them.

The following side effects are common and are experienced by up to 1 in 10 people using

Tobracin: eye redness, eye discomfort, eye allergy, itchy eyelids.

The following uncommon side effects have been reported by up to 1 in 100 people using Tobracin:

Headache, hypersensitivity reactions

Inflammation, scratching or other problems with the surface of the eye such as swelling

Impaired or blurred vision

Redness or swelling of the eyelid

Eye discharge, eye pain, dry eyes, itchy eyes, and watery eye

Problems with the skin such as abnormal sensations, inflammation of the skin, itchy or dry

skin

The appearance of patches on the skin

Loss of eye brows or eye lashes

The following side effects have also been reported but it is not known how many people

have been affected:

Skin rash or redness, eye irritation.

Keep container tightly closed after each usage.

- Eye drops: Do not store above 30 oC, Discard bottle 4 weeks after opening.

- Eye Ointment: Do not store above 30 oC.

a. What this product contains

Each 1 ml contains 3 mg Tobramycin (Active ingredient) and 0.1 Benzalkonium Chloride

(Preservative).

The other ingredients are: Boric acid, Tween 80, Sodium Sulphate, Sodium Chloride, HCl or

NaOH, Highly Purified Water.

What Tobracin Eye Ointment contains.

Each 1 g contains 3 mg Tobramycin (Active ingredient).

The other ingredients are: White petrolatum, Paraffin oil, Lanolin alcohol.

- Eye Drops: 10 ml plastic dropper bottle - Eye Ointment: Tube of 5 gm. N. B.: This ophthalmic product contains benzalkonium chloride as a preservative which may be deposited in soft contact lenses; therefore this product should not be used while wearing these lenses. These lenses should be removed before application of this product and not reinserted earlier than 15 minutes after use.