Product Description:

• Tagrisso contains the active substance osimertinib, which belongs to a group of medicines called protein kinase inhibitors which are used to treat cancer.


• TAGRISSO is used to treat adults with a type of lung cancer called ‘non-small cell lung cancer.’ If a test has shown that your cancer has certain changes (mutations) in a gene called ‘egfr’ (epidermal growth factor receptor) your cancer is likely to respond to treatment with tagrisso.

Tagrisso can be prescribed for you:

• After complete removal of your cancer as a post-surgical (adjuvant)treatment or as the first medicine you receive for your cancer that has spread to other parts of the body or in certain circumstances if you have been treated for your cancer before with other protein kinase inhibitor medicines.

How to use:

• Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.


• The recommended dose is one 80 mg tablet each day.


• If necessary, your doctor may reduce your dose to one 40 mg tablet each day.


• Tagisso is taken by mouth. Swallow the tablet whole with water. Do not crush, split or chew the tablet.


• Take tagrisso every day at the same time.


• You can take this medicine with or without food.

If you have trouble swallowing the tablet, you can mix it with water:

• Put the tablet in a glass.


• Add 50 ml (about two-thirds of a tumblerful) of still (non-fizzy) water – do not use any other liquids.


• Stir the water until the tablet breaks up into very small pieces - the tablet will not completely dissolve.


• Drink the liquid straight away.


• To make sure you have taken all of the medicine, rinse the glass thoroughly with another 50 ml of water and drink it.

How to store TAGRISSO:

• Keep this medicine out of the sight and reach of children.


• Do not use this medicine after the expiry date (exp) which is stated on the blister foil and carton.


• The expiry date refers to the last day of that month.


• This medicine does not require any special storage conditions.


• Do not use any pack that is damaged or shows signs of tampering.


• Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use.


• These measures will help protect the environment.

Caution & Warnings:

Talk to your doctor, pharmacist, or nurse before taking Tagrisso if:

• you have suffered from inflammation of your lungs (a condition called ‘interstitial lung disease’).


• If you have ever had heart problems – your doctor may want to keep a close eye on you.


• you have a history of eye problems.


• if any of the above apply to you (or you are not sure), talk to your doctor, pharmacist or nurse before taking this medicine.

Tell your doctor straight away while taking this medicine if:

• You have sudden difficulty in breathing together with a cough or fever.


• You have severe peeling of your skin.

Ingredients:

• The active substance is osimertinib (as mesylate). Each 40 mg film-coated tablet contains 40 mg of osimertinib. 


• The other ingredients are mannitol, microcrystalline cellulose, low-substituted hydroxypropyl cellulose, sodium stearyl fumarate, polyvinyl alcohol, titanium dioxide,50 macrogol 3350, talc.


• Tagrisso 40 mg is supplied as beige, film-coated, round and biconvex tablets, marked with “az” and “40” on one side, and plain on the other.