Suplasyn (hyaluronic acid (HA) is a natural component of the synovial membrane and plays an important role in maintaining the physiological internal environment of the joint.
A viscoelastic solution of the specified molecular weight of purified hyaluronic acid
Hyaluronic acid is the prototype for a wide variety of polysaccharide biopolymers (glycosaminoglycans), which are important components of all extracellular tissue structures, including cartilage and synovial fluid.
It is beneficial for osteoarthritis to reduce pain and improve the physical function of the joints.
How to use:
Depending on the size of the joint, up to 6 mL may be given intra-articularly.
It is intended for one dose only.
Follow the instructions well and stick to severe sterilization.
Discard any unused portion of the syringe. To use the prefilled syringe, remove the locking cap, attach a suitable cannula (recommended 21-25 g depending on the coupling) and secure it by turning slightly.
Caution & Warnings:
Do not give it to patients with known hypersensitivity reactions.
Follow the usual precautions and contraindications for any intra-articular injection.
Do not inject into blood vessels.
It should not be used in patients with inflammation or irritation in the joint, as it may exacerbate the symptoms of osteoarthritis.
The patient should rest 24-48 hours after the injection and avoid any strenuous activity during the full course of treatment.
Transient, short-term pain may occur after intra-articular insertion.
The affected joint may show a mild local reaction such as pain, feeling hot, hyperthermia, redness, effusion, irritation, and swelling/inflammation.
If these symptoms occur, rest the affected joint and apply ice to the affected area. Symptoms subside within days for most patients.
In some cases, mild local reactions such as pain, irritation, swelling, arthritis, and effusion may be greatly enhanced and more severe as an expression of hypersensitivity. In such cases, therapeutic intervention may be necessary, eg aspiration of joint fluid.
Local reactions can be accompanied by systemic reactions such as fever, chills, cardiovascular reactions and, in rare cases, anaphylactic reactions.
Very rarely, skin rash/pruritus, urticaria, synovitis, and hypotension have been reported following administration of the injection.
Discontinue use if adverse reactions occur. Avoid using with sterilizing or antiseptic agents containing quaternary ammonium salt solutions.
Sublacin and pregnancy and lactation
Since there is no clinical evidence for the use of Hyaluronic Acid in pregnant and lactating women, treatment with hyaluronic acid is not recommended in these patients.
Suplasyn (hyaluronic acid (HA) is a natural component of the synovial membrane and plays an important role in maintaining the physiological internal environment of the joint.
A viscoelastic solution of the specified molecular weight of purified hyaluronic acid
Hyaluronic acid is the prototype for a wide variety of polysaccharide biopolymers (glycosaminoglycans), which are important components of all extracellular tissue structures, including cartilage and synovial fluid.
It is beneficial for osteoarthritis to reduce pain and improve the physical function of the joints.
How to use:
Depending on the size of the joint, up to 6 mL may be given intra-articularly.
It is intended for one dose only.
Follow the instructions well and stick to severe sterilization.
Discard any unused portion of the syringe. To use the prefilled syringe, remove the locking cap, attach a suitable cannula (recommended 21-25 g depending on the coupling) and secure it by turning slightly.
Caution & Warnings:
Do not give it to patients with known hypersensitivity reactions.
Follow the usual precautions and contraindications for any intra-articular injection.
Do not inject into blood vessels.
It should not be used in patients with inflammation or irritation in the joint, as it may exacerbate the symptoms of osteoarthritis.
The patient should rest 24-48 hours after the injection and avoid any strenuous activity during the full course of treatment.
Transient, short-term pain may occur after intra-articular insertion.
The affected joint may show a mild local reaction such as pain, feeling hot, hyperthermia, redness, effusion, irritation, and swelling/inflammation.
If these symptoms occur, rest the affected joint and apply ice to the affected area. Symptoms subside within days for most patients.
In some cases, mild local reactions such as pain, irritation, swelling, arthritis, and effusion may be greatly enhanced and more severe as an expression of hypersensitivity. In such cases, therapeutic intervention may be necessary, eg aspiration of joint fluid.
Local reactions can be accompanied by systemic reactions such as fever, chills, cardiovascular reactions and, in rare cases, anaphylactic reactions.
Very rarely, skin rash/pruritus, urticaria, synovitis, and hypotension have been reported following administration of the injection.
Discontinue use if adverse reactions occur. Avoid using with sterilizing or antiseptic agents containing quaternary ammonium salt solutions.
Sublacin and pregnancy and lactation
Since there is no clinical evidence for the use of Hyaluronic Acid in pregnant and lactating women, treatment with hyaluronic acid is not recommended in these patients.