Product Description:

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  Sancuso (granisetron) is an antiemetic that works by blocking the actions of serotonin in the body that can trigger nausea and vomiting.

  
  


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  Prevention of nausea and vomiting caused by cancer medications (chemotherapy)

  
  

How to use:

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  The recommended dosage is a single transdermal system applied to the upper outer arm a minimum of 24 hours, up to a maximum of 48 hours, before chemotherapy.

  
  


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  The transdermal system should be worn at minimum, 24 hours after chemotherapy is finished.

  
  


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  The transdermal system can be worn for up to 7 days.

  
  

Caution & Warnings:

• Granisetron may mask a progressive ileus and/or gastric distention; consider before use in patients with abdominal surgery. Monitor for decreased bowel activity, particularly in patients with risk factors for gastrointestinal obstruction.


• Serotonin syndrome has been reported with 5-HT3 receptor antagonists alone but particularly with concomitant use of serotonergic drugs. If such symptoms occur, discontinue Sancuso and initiate supportive treatment. If concomitant use of Sancuso with other serotonergic drugs is clinically warranted, patients should be aware of a potential increased risk of serotonin syndrome.


• Mild application site reactions have occurred; remove Sancuso transdermal system if severe reactions or a generalized skin reaction occur.


• Avoid exposing Sancuso transdermal system and surrounding area to direct external heat sources, such as heating pads.


• Avoid direct exposure of application site to natural or artificial sunlight, including sunlamps, by covering with clothing throughout wear and for 10 days after removal.

Side Effects:

• Constipation

Ingredients:

• Granisetron.