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Pristiq 50mg Tablet 30
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About Product

Desvenlafaxine extended-release tablets 50 mg 

What Desvenlafaxine is used for :


  • Desvenlafaxine is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), indicated for the treatment of major depressive disorder.


Do not use Desvenlafaxine :


  • Hypersensitivity to Desvenlafaxine succinate, venlafaxine hydrochloride or any excipients

  • Do not use with an MAOI or within 14 days of stopping an MAOI.

  • Allow 7 days after stopping Desvenlafaxine before starting an MAOI


Warnings and precautions :


  • Clinical Worsening/Suicide Risk: Monitor for clinical worsening and suicide risk 

  • Serotonin Syndrome or Neuroleptic Malignant Syndrome (NMS)-like Reactions: Serotonin syndrome or NMS-like reactions have been reported with SSRIs and SNRIs.

  • Discontinue Desvenlafaxine and initiate supportive treatment

  • Elevated Blood Pressure: Has occurred with Desvenlafaxine .

  • Hypertension should be controlled before initiating treatment.

  • Monitor blood pressure regularly during treatment

  • Abnormal Bleeding: Desvenlafaxine may increase the risk of bleeding events.

  • Patients should be cautioned about the risk of bleeding associated with the concomitant use of Desvenlafaxine and NSAIDs, aspirin, or other drugs that affect coagulation 

  • Narrow-angle Glaucoma: Mydriasis has occurred with Desvenlafaxine .

  • Patients with raised intraocular pressure or those at risk of angle-closure glaucoma should be monitored 

  • Activation of Mania/Hypomania: Has occurred.

  • Use cautiously in patients with Bipolar Disorder.

  • Caution patients about the risk of activation of mania/hypomania 

  • Cardiovascular/Cerebrovascular Disease:

  • Use cautiously in patients with cardiovascular or cerebrovascular disease Cholesterol and Triglyceride Elevation:

  • Use cautiously in patients with lipid metabolism disorders. Consider monitoring serum cholesterol and triglyceride 

  • Discontinuation Symptoms: Have occurred.

  • Taper the dose when possible and monitor for discontinuation symptoms 

  • Renal Impairment: Reduces the clearance of Desvenlafaxine . Dosage adjustment is necessary in severe and ESRD. In moderate renal impairment, the dose should not exceed 50 mg/day 

  • Seizure: Can occur. Use cautiously in patients with seizure disorder 

  • Hyponatremia: Can occur in association with SIADH 

  • Drugs Containing Desvenlafaxine or Venlafaxine: Should not be used concomitantly with it

  • Interstitial Lung Disease and Eosinophilic Pneumonia: Can occur


Possible Side Effects :


  • Stop using the product and seek immediate medical attention if you develop throat tightness or swelling of the eyes, face, lips or tongue, feel faint, or have difficulty breathing.

  • Stop using the product if you develop hives or itching of the face or body. 


Other Medicines and Desvenlafaxine :


  • Especially tell your healthcare provider if you take:

  • other MAOIs

  • medicines to treat migraine headaches known as triptans

  • tricyclic antidepressants

  • fentanyl

  • lithium

  • tramadol

  • tryptophan

  • buspirone

  • amphetamines

  • St. John's Wort

  • other medicines containing Desvenlafaxine or venlafaxine

  • medicines that can affect blood clotting such as aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin

  • medicines used to treat mood, anxiety, psychotic, or thought disorders, including selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs)


How to Use Desvenlafaxine :


  • Recommended dose: 50 mg once daily with or without food.


How to Store Desvenlafaxine :


  • Store at 20° to 25°C.Do not use after the expiration date (EXP), which is on the container. 

  • The expiration date refers to the last day of that month.

  • Keep and all medicines out of the reach of children.

Product Details:

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