Product Description:

Incresync contains two different medicines in one tablet:

• The two substances are alogliptin and pioglitazone.


• Alogliptin belongs to a group of medicines called DPP ‑ Inhibitors (dipeptidyl peptidase ‑ 4 ‑ inhibitors). Alogliptin works by increasing the levels of insulin in the body after a meal and reducing the amount of sugar in the body.


• Pioglitazone belongs to a group of medicines called thiazolidinediones. It helps the body to use the insulin that is produced in a better way.


• Both of these drug groups are diabetes drugs that are taken orally.

What Incresync is used for:

• Incresync is used to lower blood sugar levels in adults with type 2 diabetes.


• Type 2 diabetes is also called non-insulin-dependent diabetes.


• Incresync is used when blood sugar cannot be adequately controlled on a diet, exercise, and other oral diabetes medicines, such as pioglitazone, or pioglitazone, and metformin together.


• Your doctor will check if Incresync is working for you 3 to 6 months after you start treatment.


• If you are already taking both alogliptin and pioglitazone as separate tablets, Incresync may replace them with one tablet.


• It is important that you continue to follow the diet and exercise advice given to you by your nurse or doctor.

How To Use:

• Follow all directions on your prescription label and read all medication guides or instruction sheets.


• Your doctor may occasionally change your dose.


• Use the medicine exactly as directed.


• You may take this medicine with or without food.


• Incresync is available as tablets and can only be obtained with a prescription.


• It is taken by mouth once daily.


• The recommended dose depends on the patient’s current treatment for diabetes.


• For more information about using Incresync, see the package leaflet or contact your doctor or pharmacist.


• Titrate dose based on glycemic response as determined by hemoglobin A1c (HbA1c).


• Maximum dose: Alogliptin 25 mg per day; Pioglitazone 45 mg per day.

Warnings And Precautions:

• Do not take Incresync:


• If you are allergic to alogliptin, pioglitazone or any of the other ingredients of this medicine.


• If you have had a severe allergic reaction to any of the medicines you are taking to control your blood sugar.


• Symptoms of a severe allergic reaction may include rash, red raised spots on the skin (hives), swelling of the face, lips, tongue and throat, which may cause difficulty in breathing or swallowing.


• Additional symptoms can include general itching and a feeling of warmth that especially affects the scalp, mouth, neck, palms and soles of the feet (Stevens-Johnson syndrome).


• If you have or have had heart failure in the past .


• If you have any liver disease.


• If you have diabetic ketoacidosis (a serious complication of poorly controlled diabetes ). Symptoms include severe thirst, frequent urination, loss of appetite, nausea or vomiting and rapid weight loss.


• If you have or have ever had bladder cancer.


• If you have blood in your urine that your doctor has not examined further. Do not take Incresync and see a doctor so that your urine can be checked as soon as possible.


• Talk to your doctor or pharmacist before taking Incresync.


• if you have type 1 diabetes (your body does not produce insulin ).


• if you are taking a diabetes medicine that is a so-called sulphonylurea (eg glipzide, tolbutamide, glibenclamide) or insulin .


• if you have a heart disease or fluid retention in your body.


• If you are taking anti-inflammatory painkillers that can also cause fluid retention and swelling, you must also tell your doctor.


• if you are older and taking insulin , as you may be at increased risk for heart problems.


• if you have liver or kidney problems.


• Before you start taking this medicine, you must submit a blood sample that is used to test your liver and kidney function. This check can be repeated at regular intervals.


• If you have kidney disease, your doctor may need to lower your Incresync dose .


• if you have a specific type of diabetes-related eye disease called macular edema (swelling of the back of the eye).


• if you have ovarian cysts ( polycystic ovary syndrome ).


• The risk of getting pregnant may increase as ovulation may start again when you take Incresync.


• If this applies to you, use an appropriate method of contraception to avoid an unplanned pregnancy.


• if you have or have had pancreatic disease.

Ingredients:

• Alogliptin + Pioglitazone

Product Details:

• Brand: Incresync
• Product Form: Tablets
• Product Type: Tablets