Glibenclamide 5 mg tablets

What Glibenclamide is used for:

Glibenclamide (also known as Glyburide) is used to lower blood sugar levels in patients with diabetes mellitus type 2 (non-insulin dependent) along with a proper diet and exercising.

Do not take Glibenclamide:

• If you’re allergic to the active substance, sulfonylurea, sulfonamides or any other component of this medicine.
• If you have diabetes mellitus type I (insulin dependent).
• If you have diabetic ketoacidosis (an emergency condition where your blood sugar levels are very high and you experience nausea, frequent urination, fatigue and muscle weakness).
• If you are in a diabetic coma.
• If you have severe liver problems.
• If you have kidney problems.
• If you are taking a medicine called Bosentan for high blood pressure. 

Warnings and precautions:

Talk to your doctor about all your medical conditions before taking this medicine including:

• If you are recovering from an injury, operation, infections with fever, or from other forms of stress.
• If you have liver or kidney problems.
• If you have a deficiency in an enzyme called glucose-6-phosphate dehydrogenase (G6PD).
• If you have a heart disease.
• This medicine may cause low blood sugar levels (hypoglycemia) especially if you miss a meal, exercise more or drink alcohol. Symptoms include: nausea, hunger, shaking, dizziness, confusion, sleepiness, restlessness, difficulty speaking and sweating. You may take a sugar cube or some sweet juice to help it.

Possible side effects:

Stop using this product and seek immediate medical help if you develop rash; hives; itching; red, swollen, blistered, or peeling skin; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

Serious side effects:

• Allergic reactions
• Hypoglycemia
• Liver problems

Other medicines and Glibenclamide:

Glibenclamide interacts with a lot of medicines including:

• Medicines to treat pain and inflammation.
• Other medicines to treat diabetes
• Anticoagulants such as Warfarin
• Medicines used for high blood pressure
• Medicines used for irregular heartbeat
• Medicines used to lower blood cholesterol
• Medicines used to treat mood disorders
• Some antibiotics
• Anti-fungals
• Medicines to treat cancer
• Oral contraceptives
• Medicines to treat asthma and nasal congestion
• Steroids 
• Medicines to treat stomach ulcers like Cimetidine
• Phenytoin
• Bosentan

How to take Glibenclamide :

• This medicine is intended for adults only.
• Take as indicated by your doctor.
• Take with food, with the first meal of the day.
• The usual starting dose is 2.5 – 5 mg once daily.
• Your doctor may gradually increase the dose up to 20 mg per day, as one or two doses daily. 

How to store Glibenclamide:

• Store at room temperature 68 to 77°F (20 to 25°C).
• Keep this medicine out of reach of children.
• Do not use this medicine after the expiry date stated on the package. The expiry date refers to the last day of that month.