Product description:

Cefim has been shown to be active against most strains of the following grampositive and gramnegative organisms:

• streptococcus pneumonia, streptococcus pyogenes, streptococcus agatactiae, haemophilus influenzae, haemophilus parainfluenza, moraxella (branhamella) catarrhalis, escherichia coli, proteus mirabilis.


• proteus vulgaris, neisseria gonorrhoeae, klebsiella pneumonia, klebsiella oxytoca, pasteurella multocida, providencia species, salmonella species, shigella species, citrobacter diversus, serratia marcescens.

cefim is indicated in the treatment of the following:

• Pharyngitis, tonsillitis, and sinusitis.


• Acute bronchitis and acute exacerbations of chronic bronchitis.


• Otitis media.


• Uncomplicated urinary tract infections.


• Uncomplicated urethral or cervical gonorrhea.

How To Use:

Dosage & administration:
adults:

• The recommended dose of cefim is 400 mg daily.

This may be given as a 400 mg capsule once daily or as a 200 mg capsule every 12 hours.
For the treatment of uncomplicated urethral or cervical gonococcal
infections:

• A single oral dose of 400 mg is recommended.

Caution & Warnings:

• Before starting therapy with cefixime it should be ascertained if there have been any previous hypersensitivity reactions to cephalosporins or penicillins.


• In the event of allergic reactions administration of the drug should be suspended and the patient should receive opportune treatment.


• As pseudomembranous colitis may appear during treatment with broadspectrum antibiotics (including macrolides, semisynthetic penicillins and cephalosporins), the onset of this form of colitis should be


• Taken into consideration during treatment with these drugs.


• Extreme care should be taken when administering cefim to patients with severe renal


• In such cases, the dose should be lower than the normally recommended one.


• Broadspectrum antibiotics should be administered with extreme care to patients who have previously suffered from intestinal disorders as antibiotic therapyassociated colitis could develop.

Precautions:

• prolonged use of antibiotics may result in overgrowth of nonsusceptible organisms.

Usage during pregnancy and lactation:

• There are no adequate and wellcontrolled studies on pregnant women;
  therefore, this drug should be used during pregnancy only if, it clearly


• It is not known whether cefixime is excreted in human milk.

Ingredients:

• Cefim400: each capsule of cefim400 contains 400 mg cefixime (as trihydrate).