Product Description:

• Vortioxetine is an antidepressant that is used to treat major depressive disorder in adults.


• This medication is used to treat depression.


• It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Vortioxetine is an SSRI (selective serotonin reuptake inhibitor) and serotonin receptor modulator.


• This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living.

How To Use:

• Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

Usual Adult Dose for Depression:

Initial dose:

10 mg orally once a day.

Maintenance dose:

• 5 to 20 mg orally once a day

Maximum dose:

• 20 mg/day

Comments:

• Patients should be screened for bipolar disorder, mania, and hypomania prior to starting treatment.


• Patients who do not tolerate higher doses may be maintained on 5 mg orally once a day.

Use: Treatment of major depressive disorder (MDD)

Usual Adult Dose for Major Depressive Disorder:

Initial dose:

• 10 Mg Orally Once A Day.

Maintenance dose:

• 5 To 20 Mg Orally Once A Day.

Maximum dose:

• 20 Mg/Day.


• For elderly people 65 years of age or older, the starting dose is 5 mg vortioxetine taken once daily.

Comments:

• Patients should be screened for bipolar disorder, mania, and hypomania prior to starting treatment.


• Patients who do not tolerate higher doses may be maintained on 5 mg orally once a day.


• Vortioxetine can be discontinued abruptly, but a decrease to 10 mg a day is recommended for patients who are on 15 mg a day or more for one week before complete discontinuation.

Warnings And Precautions:

• 10 Vortioxetine is in pregnancy category C.


• There is no data on its effects with breastfeeding.

Before taking vortioxetine, tell your doctor or pharmacist if:

• you are allergic to it; or if you have any other allergies.


• This product may contain inactive ingredients, which can cause allergic reactions or other problems.

Before using this medication, tell your doctor or pharmacist:

• Your medical history, especially of: personal or family history of bipolar/manic-depressive disorder, personal or family history of suicide attempts, seizures, low sodium in the blood, intestinal ulcers/bleeding (peptic ulcer disease) or bleeding problems, personal or family history of glaucoma (angle-closure type).


• Do not drive, use machinery, or do anything that needs alertness until you can do it safely.


• Older adults may be more sensitive to the side effects of this drug, especially bleeding.


• Older adults may also be more likely to develop a type of salt imbalance (hyponatremia), especially if they are also taking "water pills" (diuretics) with this medication.

During pregnancy:

• This medication should be used only when clearly needed.


• It may harm an unborn baby. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop withdrawal symptoms such as feeding/breathing difficulties, seizures, muscle stiffness, or constant crying.


• if you notice any of these symptoms in your newborn, tell the doctor promptly.

Ingredients:

Brintellix 10 mg film-coated tablet:

• 7Yellow, almond-shaped. Film-coated tablets marked with “TL” on one side and “10” on the


• Other side.

Brintellix 20 mg film-coated tablet:

• Red, almond-shaped film-coated tablet marked with “TL” on one side and “20” on the other side.

Brintellix film-coated tablets are available in blister packs of 28.

Product Details: